Characteristics that a microbe must possess to cause infection in human

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In order to cause infection, a successful pathogen must be able to:

  • Enter and establish in the human host
  • Acquire nutrients from the host
  • Avoid or circumvent the host’s innate defenses and a powerful immune system
  • Multiply in numbers
  • Disseminate to a preferred site, if necessary and eventually
  • Be transmitted to a new susceptible host

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